PA4013 Biomedical Plastics Syllabus:

PA4013 Biomedical Plastics Syllabus – Anna University PG Syllabus Regulation 2021

OBJECTIVES:

 To learn about various types of biopolymers produced from starch and microbes.
 To understand various natural and synthetic polymers used for biomedical applications.
 To learn about the plastics that are used as implants in cardiovascular, dental, ophthalmology, and other artificial organs.
 To be familiarized with evaluation methods of biomedical polymers and their interaction with human system in in-vivo and in-vitro environments.
 To understand various natural and synthetic polymers used for biomedical applications and their compatibility with biological system

UNIT I MATERIALS USED IN MEDICINE

Introduction, Polymers, Silicone Biomaterials: History and Chemistry, Medical Fibers and Biotextiles, Hydrogels, Bioresorbable and Bioerodible Materials, Natural Materials, Metals, Ceramics, Glasses, and Glass-Ceramics, Composites, Textured and Porous Materials, Surface-Immobilized Biomolecules

UNIT II BIOLOGICAL TESTING OF BIOMATERIALS

Introduction to Testing Biomaterials, In Vitro Assessment of Tissue Compatibility, In Vivo Assessment of Tissue Compatibility, Evaluation of Blood-Materials Interactions, Microscopy for Biomaterials Science

UNIT III DEGRADATION OF MATERIALS IN BIOLOGICAL ENVIRONMENT

Introduction: Degradation of Materials in the Biological Environment, Chemical and Biochemical Degradation of Polymers, Degradative Effects of the Biological Environment on Metals and Ceramics, Pathological Calcification of Biomaterials

UNIT IV APPLICATION OF MATERIALS IN MEDICINE, BIOLOGY, AND ARTIFICIAL ORGANS

Introduction, Non thrombogenic Treatments and Strategies, Cardiovascular Medical Devices, Implantable Cardiac Assist Devices, Extracorporeal Artificial Organs, Orthopedic Applications, Dental Implantation, Adhesives and Sealants, Ophthalmological Applications, Intraocular Lens Implants, Burn Dressings and Skin Substitutes, Sutures, Drug Delivery Systems, Cochlear Prostheses, Biomedical Sensors and Biosensors, Overview of Tissue Engineering, Synthetic Bioresorbable Polymer Scaffolds.

UNIT V PRACTICAL ASPECTS OF BIOMATERIALS

Introduction, Sterilization of Implants and Devices, Implant and Device Failure, Correlation, Surfaces and Biomaterials Science, Development and Regulation of Medical Products Using Biomaterials, Ethical Issues in the Development of New Biomaterials, Legal Aspects of Biomaterials

TOTAL: 45 PERIODS

OUTCOMES:

At the end of the course, students will be able to
 Understand the production of bio-plastics from bio-based feed stocks.
 Know about various plastics that are used for biomedical applications such as cardiovascular, dental, ophthalmology, and other artificial organs.
 Understand the methods and standards used for the evaluation of biomedical polymers.
 Describe the criteria for the selection of biomedical polymers
 Explain the biomedical applications of polymers

REFERENCES

1. Ratner, B.D., Hoffman, A.S., Schoen, F.J. and Lemons, J.E., 2004. Biomaterials science: an introduction to materials in medicine. Elsevier.
2. Park, J.B., 2012. Biomaterials science and engineering. Springer Science & Business Media.
3. Williams, D., 2014. Essential biomaterials science. Cambridge University Press.
4. Pignatello, R. ed., 2011. Biomaterials science and engineering