NT4012 Nanotechnology in Health Care Syllabus:

NT4012 Nanotechnology in Health Care Syllabus – Anna University PG Syllabus Regulation 2021

OBJECTIVES

 To be introduced to recent advancements in nano medicine.
 To learn about nano diagnostics.
 To learn developments in nanostructured materials used for medical implants.

UNIT I TRENDS IN NANOBIOTECHNOLOGY

Nanotechnology in gene therapy. Stem Cell technology. PCR, ELISA, DNA Profiling and Blotting techniques-Nanoprobes.

UNIT II NANOIMMUNOTECHNOLOGY

Nanoimmuno assay and nano-immuno sensors- Bio-Barcode Assay- use of magnets, gold, DNA and antibodies. Immunodiagnostics for cancer and central nervous system disorders.

UNIT III NANOTECHNOLOGY BASED MEDICAL DIAGNOSTICS

Improved diagnosis by in vivo imaging – detection of tumors, plaque and genetic defects. Nanobot medical devices. Cantilever Sensors.

UNIT IV PROSTHETIC AND MEDICAL IMPLANTS

Prosthesis and implants. neural, ocular, cochlear, dental implants. implants and prosthesis of skin, limb, bone. Artficial organ and Organ transplant. Nano fibre scaffold technology.

UNIT V BIOMEDICAL APPLICATIONS OF NANOTECHNOLOGY

Nano-bioconjugates and their significance. Nanoscaffolds. Magnetic Nanoparticles. Multifunctional Inorganic and organic nanoparticles and their biomedical applications.

TOTAL : 45 PERIODS

COURSE OUTCOMES:

CO1: Comprehend the nanoparticles-based gene therapy, nanoprobing and profiling techniques and their application
CO2: Understand the use of metal nanoparticles and antibodies in diagnosis of biomarkers with high sensitivity
CO3: Be aware of the principle and uses of cantilever sensors and imaging of plaques and tumors
CO4: Completely understand the ocular, cochlear, dental implants and nanofiber technology
CO5: Have knowledge on functionalised nanoscaffolds, magnetic, organic and inorganic nanoparticles

REFERENCES:

1. Brian, R Eggins, Chemical Sensors and Biosensors; Wiley; New York, 2002.
2. 2. L Gorton, Biosensors and modern biospecific analytical techniques, Wilson & Wilson’s Comprehensive Analytical Chemistry Elsevier, Amsterdam, London; 2005.
3. David Wild; The Immunoassay Handbook; 3rd ed.; Amsterdam: Elsevier; 2005.
4. Allen J Bard and LarryR Faulkner;Electrochemical Methods: Fundamentals and Applications; Wiley, New York, 2nd ed.; 2001.
5. Vladimir M. Mirsky, Ultrathin Electrochemical Chemo- and Biosensors: Technology and Performance in Springer Series on Chemical Sensors and Biosensors; Springer, Berlin; 2004