CD4091 Bio Materials Syllabus:
CD4091 Bio Materials Syllabus – Anna University PG Syllabus Regulation 2021
OBJECTIVES:
To study different concepts in selecting bio and smart materials
To import knowledge on different electro-rheological and piezoelectric materials
To import knowledge on different shape memory materials and their applications of materials in biomedical engineering and special materials for actuators, sensors, etc.
To import knowledge on Materials for oral and maxillofacial surgery
To import knowledge on materials for cardiovascular ophthalmology and skin regeneration.
UNIT I INTRODUCTION
Human anatomy- tissues- organs- repair- regeneration- Wolff’s Law – biomaterial – compatibility – classification- Biomimetics – Material response: swelling and leaching, corrosion and dissolution, deformation and failure, friction and wear – host response: the inflammatory process – coagulation and hemolysis- in vitro and in vivo evaluation of
biomaterials – Testing and validation- government regulatory bodies.
UNIT II DENTAL MATERIALS
Teeth composition, formation and properties – temporary fixation devices -classification –– biomaterials used- metals and alloys- Fillings and restoration materials – oral and maxillofacial surgery – dental cements and dental amalgams – dental adhesives.
UNIT III ORTHOPAEDIC MATERIALS
Bone composition, formation and regeneration – properties – defects – temporary fixation devices – joint replacement – biomaterials used in bone and joint replacement metals and alloys- stress shielding effect- bone tissue engineering.
UNIT IV WOUND DRESSING MATERIALS AND SURGICAL AIDS
Skin structure – defects ( burn, ulcer, trauma etc) and disease- skin regeneration – classification of regenerative material – Sutures- Adhesives – classification – Surgical tools materials – sterilization – Laparoscopic tools
UNIT V CARDIOVASCULAR, OPTHALMOLOGY AND DRUG DELIVERY MATERIALS
Blood clotting – blood theology– approaches to thrombo resistance materials development– blood vessels – The heart – aorta and valves – geometry of blood circulation – cardiac pacemakers – extracorporeal blood circulation devices. lungs – vascular implants: vascular graft, cardiac valve prostheses – Eye- defects – correction- Biomaterials in opthalmology – drug delivery methods and materials.
OUTCOMES:
On Completion of the course the student will be able to
Use of Bio materials for cardiovascular Opthalmology and Skin Regeneration
Use of Bio materials for Dental & Bone application
Use of shape memory alloys in engineering application
Explain the characteristics of Bio and smart materials
Use of smart materials as sensors, actuators.
REFERENCES:
1. M. V. Gandhi and B. S. Thompson, “Smart Materials and Structures”, Chapman and Hall, London, First Edition, 1992.
2. Sujata V., Bhat., “Biomaterials”, Narosa Publication House, New Delhi, 2002.
3. Buddy D. Ratner (Editor), Allan S. Hoffman (Editor), Frederick J. Schoen (Editor), Jack E. Lemons, “Biomaterials Science: An Introduction to Materials in Medicine”, Academic Press,2nd edition, 2004.
4. Duerig,T. W., Melton, K. N, Stockel, D. and Wayman, C.M., “Engineering aspects of Shapememory Alloys”, Butterworth – Heinemann, 1990.
5. Mohsen Shahinpoor and Hans-Jo¨rg Schneider “Intelligent Materials”, RSC Publishing,2008.