BO4014 Nanobiotechnology Syllabus:
BO4014 Nanobiotechnology Syllabus – Anna University PG Syllabus Regulation 2021
OBJECTIVES
The course aims to,
• provide fundamental concepts of nanotechnology.
• use the fundamental knowledge for the application of nanotechnology to biological sciences including nanomedicine.
• To gain knowledge on the characterization of nanomaterials.
• To understand the principle and protocol for nano characterization equipments.
UNIT I NANOSCALE AND NANOBIOTECHNOLOGY
Introduction to Nanoscience and Nanotechnology; Milestones in Nanotechnology; Overview of Nanobiotechnology and Nanoscale processes; Physicochemical properties of materials in Nanoscales.
UNIT II FABRICATION AND CHARACTERIZATION OF NANOMATERIALS
Types of Nanomaterials (Quantum dots, Nanoparticles, Nanocrystals, Dendrimers, Buckyballs, Nanotubes); Gas, liquid, and solid –phase synthesis of nanomaterials ;Lithography techniques (Photolithography, Dip-pen and Electron beam lithography); Thin film deposition; Electrospinning. Biosynthesis of nanomaterials.
UNIT III PROPERTIES AND MEASUREMENT OF NANOMATERIALS
Optical Properties: Absorption, Fluorescence, and Resonance; Methods for the measurement of nanomaterials; Microscopy measurements: SEM, TEM, AFM and STM. Confocal and TIRF imaging.
UNIT IV PROPERTIES AND MEASUREMENT OF NANOMATERIALS
Properties of DNA and motor proteins; Lessons from nature on making nanodevices; Reactive groups on biomolecules (DNA & Proteins); Surface modification and conjugation to nanomaterials. Fabrication and application of DNA nanowires; Nano fluidics to solve biological problems.
UNIT V NANO DRUG DELIVERY AND NANOMEDICINE
Properties of nano carriers; drug delivery systems used in nanomedicine; Enhanced Permeability and Retention effect; Blood-brain barrier; Active and passive targeting of diseased cells; Health and environmental impacts of nanotechnology.
TOTAL: 45 PERIODS
COURSE OUTCOME
At the end of the course the student will be able to,
CO1 Understand fundamental concepts of nanotechnology and nanomaterials
CO2 Have knowledge on the fabrication and characterization of nanomaterials
CO3 Understand nanobiology and modification of nanomaterials
CO4 Know nano-based drug delivery and nanomedicine
REFERENCES
1. Nanobiotechnology: Concepts, Applications and Perspectives, Christ of M. Niemeyer(Editor), Chad A.Mirkin (Editor) , Wiley-VCH; 1 edition, 2004.
2. Nano Biotechnology: BioInspired Devices and Materials of the Future by OdedShoseyovandIlan Levy, Humana Press; 1 edition 2007.
3. Nano Biotechnology Protocols (Methods in Molecular Biology) by Sandra J Rosenthal And David W.W right , Humana Press; 1 edition, 2005.
4. Bio-Nanotechnology Concepts and applications. Madhuri Sharon, Maheshwar Sharon, Sunil Pandey and Goldie Oza, Ane Books Pvt Ltd, 1 edition 2012.
5. Microscopy Techniques for Material Science. A. R. Clarke and C. N. Eberhardt (Editors) CRC Press. 1stEdition, 2002.