BO4013 Novel Drug Delivery Systems Syllabus:
BO4013 Novel Drug Delivery Systems Syllabus – Anna University PG Syllabus Regulation 2021
OBJECTIVES:
To enable the students to
Understand the properties of polymer and its significance in drug delivery systems.
Interpret physicochemical properties of the drug with the drug delivery system
modules.
Apply the concepts of newer method of drug delivery systems involved in the pharmaceutical sciences and relevance of their drug delivery strategies.
To gain knowledge on targeted drug delivery systems
UNIT I POLYMERS
Polymers used in controlled drug delivery modules – Classification – Advantages and disadvantages of polymers – Polymer Characterisation – Various classes of controlled release systems.
UNIT II SUSTAINED RELEASE FORMULATIONS
Introduction, concept, advantages and disadvantages. Physicochemical and biological properties of drugs relevant to sustained release formulations.
UNIT III TRANSDERMAL DRUG DELIVERY SYSTEMS
Permeation through skin – factors affecting permeation – basic components of TDDS – permeation enhancers – formulation approaches used in development of TDDS and their evaluation.
UNIT IV TARGETED DRUG DELIVERY SYSTEMS
Concepts – Advantages and disadvantages – Nanoparticles – Liposomes – Microspheres – Magnetic microspheres.
UNIT V DRUG DELIVERY LARGE MOLECULES
Delivery system for Peptides and Proteins – Delivery of nucleic acids – Antibodies and siRNA.
TOTAL : 45 PERIODS
OUTCOMES:
The student will be able to
CO1. Understands the properties, importance and influence of polymers in novel drug delivery systems.
CO2. Gains the importance of various physicochemical and biological properties of the drug with the drug delivery systems.
CO3. Discuss the concepts of transdermal drug delivery systems.
CO4. Relate the importance of various targeted drug delivery systems.
CO5. Illustrate the concepts of large molecules based delivery systems.
CO6. Apply the knowledge in developing various drug delivery modules
REFERENCES:
1. Vyas S.P., Khar R.K, “Targeted & Controlled Drug Delivery: Novel Carrier Systems”, CBSPD, 2006.
2. Junginger H.E “Drug Targeting and Delivery- concepts in dosage form design” Ellis Harwood series in Pharmaceutical Technology
3. Vasant Ranade , mannfred A Hollinger “Drug delivery systems” II ed , CRC Press.
4. Grietje Molema and Dirk K F Meijer “Drug Targetting organ-specific strategies” WILEYVCH , 2001
5. Anya M Hillery et al “ Drug Delivery and Targeting”, CRC Press, 2010.