BO4006 Chemistry of Natural Products Syllabus:
BO4006 Chemistry of Natural Products Syllabus – Anna University PG Syllabus Regulation 2021
COURSE OBJECTIVES:
The course aims to,
Enhancetheoreticalknowledgeofstudentsinthechemistryofnaturalproducts
Explore this knowledge for practical applications.
UNIT I CARBOHYDRATES AND RELATED COMPOUNDS
Sugars and sugar containing drugs, polysaccharides and polysaccharide containing drugs, cellulose gums and mucilages, pectin.
UNIT II GLYCOSIDES AND TANNINS
Biosynthesis of glycosides, Phenol and alcohol glycosides, anthraquinone glycosides, cyanophore glycosides, saponin glycosides, cardiac glycosides, isothiocyanate flavonol lactone glycosides, tannins, volatile oils, resins and resin combinations.
UNIT III ALKALOIDS AND PURINES
Pyridine and piperidine alkaloids, Tropane alkaloids, Quinoline Alkaloids, isoquinoline alkaloids, Indole alkaloids, Imidazole alkaloids, Steroidal alkaloids, Alkaloidal amines and purine bases. Chemistry and structural elucidation of uric acid, interrelation between caffeine, theophylline and theobromine.
UNIT IV VITAMINS, TERPENOIDS AND FLAVONOIDS
Chemistry, medicinal and pharmaceutical uses of vitamin A, D, E, K, B1, B2, B6, B12 and Folic Acid. Chemistry and structural elucidation of Terpenes, camphor, menthol, carotenes. Classification and application of flavonoids (hespiridine, rutin, quercetin).
UNIT V MOLECULES FROM NATURAL SOURCES
Classification of Drug molecules of Plant/marine/microbial and animal sources – cytotoxic / antineoplastic agents, cardiovascular drugs – antimicrobial substances – anti-inflammatory and antispasmodic agents.
TOTAL :45 PERIODS
COURSEOUTCOMES:
At the end of the course the student will be able to,
CO1: Comprehend the medicinally important carbohydrates and related compounds from natural origin
CO2: Explain the biosynthetic pathways and chemistry of important secondary metabolites including glycosides and alkaloids.
CO3: Obtain knowledge on vitamins, terpenoids and flavonoids and some harmaceutically important molecules from natural sources.
REFERENCES:
1. Evans, W.C., ‘Trease and Evans Pharmacognosy’, 16thEdition, Saunders, 2009.
2. Wallis, T.E. “Textbook of Pharmacognosy”, 5th Edition, CBS Publishers, 2005.
3. Kokate, C.K. “Pharmacognosy”, 29thEdition, Nirali Prakashan, 2004.
4. O.P. Agarwal, Chemistry of Natural Products (Vol.-1 & 2), 41st edition, Goel publishing House, 2014.
5. Varro E. Tyler, Lynn R. Brady, James E. Robbers, Pharmacognosy, 9th edition, Published by Lea & Febiger, 2011.
6. Gurdeep Chatwal, Organic Chemistry of Natural Products (Vol. 1 & 2), Himalaya Publishing House, 2015.
7. I.L.Finar, “Organic chemistry” Volume 2, 5th edition, Published by Pearson India, 2012.