MX4010 Biomems and Artificial Organs Syllabus:
MX4010 Biomems and Artificial Organs Syllabus – Anna University PG Syllabus Regulation 2021
COURSE OBJECTIVES:
To understanding of the basics with current advancement and challenges associated with operations
To understand the uses of bioinstrumentation, processes for microelectromechanical systems and their applications in the biomedical areas
To give a basic idea of the artificial organs that can aid a human to live a normal life.
To comprehend the processes and challenges involved in implants and prosthesis using alloys.
To determine and selection of right materials for its bio applications
UNIT I INTRODUCTION
Historical perspective, Development of MEMS Technology, MEMS Technology: Present, Future and Challenges, MEMS Applications, Comparison of MEMS and Microelectronics.
UNIT II SENSORS AND ACTUATORS
MEMS Actuators, MEMS Sensing, Electron Tunneling, Sensor Noise, MEMS Physical Sensors, MEMS Chemical Sensors, Classification of Physical Sensors, Integrated, Intelligent or Smart sensors, Bio Sensing Principles and Sensing Methods, Biosensors Arrays and Implantable devices.
UNIT III ARTIFICIAL ORGANS / IMPLANTS
Artificial Heart, Prosthetic Cardiac Valves, Artificial lung (oxygenator), Artificial Kidney (Dialyser membrane) – Wearable artificial kidney, Dental Implants. Artificial Organs design and simulation – Case study – Design of artificial pancreas.
UNIT IV REPLACEMENT DEVICES FOR RESPIRATORY AND DIGESTIVE SYSTEM
Artificial lung versus natural lung – Lung replacement devices – Tracheal replacement devices – Laryngeal replacement devices – Artificial esophagus – Liver functions: Hepatic failure, Liver support systems, General replacement of liver functions – Endocrine pancreas and insulin secretion – Diabetes – Insulin therapy – Insulin administration systems
UNIT V TISSUE REPLACEMENT IMPLANTS
Soft-tissue replacements, sutures, surgical tapes, adhesive, and Dental implants – Fracture plates – Joint and Spinal replacement – Artificial skin: Current treatment for skin loss, Design principles for skin replacement – Ear and Eye implants.
45 PERIODS
PRACTICAL EXERCISES: 30 PERIODS
1. Simulation of structures for MEMS sensors
2. Designing of MEMS based accelerometer
3. Modeling and simulation of MEMS biosensor
4. Designing of micro cantilever for medical application
5. Modeling and simulation of chemical sensor
6. Modeling and simulation of prosthetic heart valves
7. Modeling and simulation of dialyzer membrane for hemodialysis
8. Modeling and stress analysis of dental implants.
9. Modeling and simulation of artificial joints.
10. Designing of bone plates and comparison of its mechanical properties with selected biocompatible materials
COURSE OUTCOMES:
CO1: Compare and explain about the characteristics of MEMs Physical and chemical sensor
CO2:Classify the biosensors according to its working principle and discuss its application as an implantable device
CO3: Design various grafts for tissue repair and artificial organs.
CO4: Enumerate biomaterials for implants, soft and hard tissue 5 replacements
CO5: Recall the cell-biomaterial interactions for constructing artificial organs
TOTAL:75 PERIODS
REFERENCES
1. BioMEMS and Biomedical Nanotechnology, volume III Tejaldesai, sangetha Bhatia
2. Gerald Miller , “Artificial Organs”, Morgan and Claypool Publisher, Narosa Publishing HouseWilliston, 2006.
3. Wanjun Wang, Stephen A.Soper, BioMEMS: Technologies and Applications, CRC Press, New York, 2007..
4. Joseph D, Bronzino, Donald R. Peterson , “The biomedical engineering handbook”, CRC Press Taylor and Francis,, 2015.